High-Grade surface osteosarcoma

Summary
Description

High grade periosteal osteosarcoma (also known as high grade surface osteosarcoma) accounts for less than 1% of all osteosarcoma. The only difference between conventional osteosarcoma and high-grade per osteal osteosarcoma is the location of the latter on the surface of the bone.

Brief description of the xray
High grade periosteal osteosarcoma appears malignant on plain x-ray. There is irregular cortical destruction as well as irregular periosteal reaction.
Tumor Name
High-Grade Surface Osteosarcoma
Tumor Type
Tumors of Bone
Benign or Malignant
Malignant
Most Common Bones
femur
Periosteal reaction
present
Position within the bone
surface
Tumor behavior
aggressive
Tumor density
mixed
Complete Information on this Tumor
Introduction and Definition

High grade periosteal osteosarcoma (also known as high grade surface osteosarcoma) accounts for less than 1% of all osteosarcoma. The only difference between conventional osteosarcoma and high-grade per osteal osteosarcoma is the location of the latter on the surface of the bone.

X-Ray Appearance and Advanced Imaging Findings
High grade periosteal osteosarcoma appears malignant on plain x-ray. There is irregular cortical destruction as well as irregular periosteal reaction. Bone marrow infiltration is visible on MRI.
Histopathology findings
High grade periosteal osteosarcoma appears identical to conventional osteosarcoma microscopically.
Treatment Options for this Tumor
The tumors are treated similarly to conventional osteosarcoma and have the same prognosis.
Suggested Reading and Reference
References
Bloem, JL and HM Kroon, Osseous Lesions, Radiologic Clinics of North America, 31(2):261-277, March 1993.

Bullough, Peter, Orthopaedic Pathology (third edition), Times Mirror International Publishers Limited, London, 1997.

Huvos, Andrew, Bone Tumors: Diagnosis. Treatment and Prognosis, W.B. Saunders, Co., 1991.